Enzo Biochem, Inc. (NYSE:ENZ) announced today a co-marketing partnership between its Enzo Life Sciences subsidiary of Farmingdale, New York, a world leader in non-radioactive probe technology, and BioTek Instruments of Winooski, Vermont, a privately held global leader in the development, manufacture and sale of microplate instrumentation for drug discovery and life science applications, involving powerful, integrated solutions for high throughput live cell analysis.Aimed at research institutions, as well as biotechnology and pharmaceutical companies, this reagents-instrumentation collaboration creates a highly reproducible and reliable platform for live cell analysis, offering a cost effective alternative to dedicated microplate imaging-based systems, which often are too costly for investigators to implement.The collaboration will be formally launched next month at MipTec 2009 in Basel, Switzerland with the presentation of the scientific poster, entitled “A cost-effective workflow for high-throughput screening of G-Protein-Coupled Receptors (GPCRs).” The poster details the use of Enzo’s new FluoForte™ Calcium Assay Kit for monitoring intracellular calcium mobilization with BioTek’s Synergy™ Mx Monochromator-based Multi-Mode Microplate Reader.Drugs targeting GPCRs represent the core of modern medicine, accounting for the majority of the best-selling drugs and roughly 40% of all prescription pharmaceuticals on the market today. Using BioTek’s Precision™ XS Automated Sample Processor for all dispensing steps in conjunction with Enzo’s proprietary calcium indicator dye technology and Synergy Mx Microplate Reader provides a small-scale, cost effective, automated cell-based screening approach for identifying GPCR agonists and antagonists. The described assay workflow provides low sample-to-sample variability and excellent assay performance in a miniaturized format.“Through this collaboration, researchers will be able to obtain integrated instrumentation and reagent solutions that are high-performance, yet affordable,“ said Wayne Patton, PhD, Chief Scientific Officer for Enzo Life Sciences. “The collaboration will provide validated turn-key solutions to the research community.”“Previously, a major source of frustration for many researchers has been that selected assays were not compatible with a particular instrument and vice-versa,” said Peter Banks, PhD, Scientific Director for BioTek Instruments. “Our companies each provide key expertise and capabilities in the live-cell analysis arena bringing together BioTek’s capabilities in microplate and dispensing technology that matches perfectly with Enzo’s cutting-edge live cell analysis reagents and kits.”About EnzoEnzo Biochem is engaged in the research, development, manufacture and licensing of innovative health care products and technologies based on molecular biology and genetic engineering techniques, and in providing diagnostic services to the medical community. Enzo’s Life Sciences division develops, produces and markets proprietary labeling and detection products for gene sequencing, genetic analysis and immunological research among others. Its catalog of over 30,000 products serves the molecular biology, drug discovery and pathology research markets. The Company’s therapeutic division is in various stages of clinical evaluation of its proprietary immune regulation medicines for uveitis and Crohn’s disease and conducts pre-clinical research on several candidate compounds aimed at producing new mineral and organic bone, including technology that could provide therapy for osteoporosis and fractures, among other applications. Enzo’s Clinical Labs division provides routine and esoteric reference laboratory services for physicians in the New York Metropolitan and New Jersey areas. Underpinning the Company’s technology and operations is an extensive intellectual property estate in which Enzo owns or licenses over 240 patents worldwide, and has pending applications for over 200 more. For more information visit our website www.enzo.com(link is external).About BioTek InstrumentsBioTek Instruments, Inc., headquartered in Winooski, VT, USA, is a worldwide leader in the design, manufacture, and sale of microplate instrumentation and software. The company has distribution in over 70 countries and an installed base of 75,000 instruments. BioTek instrumentation is used to aid in the advancement of life science research, facilitate the drug discovery process and to enable cost-effective quantification of disease relevant molecules in the clinic.Safe Harbor StatementExcept for historical information, the matters discussed in this news release may be considered “forward-looking” statements within the meaning of Section 27A of the Securities Act of 1933, as amended and Section 21E of the Securities Exchange Act of 1934, as amended. Such statements include declarations regarding the intent, belief or current expectations of the Company and its management. Investors are cautioned that any such forward-looking statements are not guarantees of future performance and involve a number of risks and uncertainties that could materially affect actual results. The Company disclaims any obligations to update any forward-looking statement as a result of developments occurring after the date of this press release.Source: BioTek. Enzo. Farmingdale, NY, and Winooski, VT, October 2, 2009 —
Leaning against the mountain, I watched the dark clouds gathering. Precipitation had always been a force in shaping these old mountains, and after a lifetime of outdoor adventure, I realized that these mountains had also shaped me.I didn’t always follow the outdoor path. While at the University of Tennessee, I didn’t exercise, drank heavily, and ate badly. The natural fitness of youth melted away in a merry-go-round of beer and pizza.Then a newfound friend and experienced backpacker, Calvin Milam, suggested I go to the Smokies with him. I was the epitome of ignorance: a suburban Memphis punk who had never camped out a day in my life. Everything was new – the weight of the pack on my shoulders, the pounding on my feet, the slow travel, the seemingly ceaseless climbs.But I was up for the challenge. For most of us the competition stops after high school—but not for those who explore the outdoors. I was still seeking to compete against myself and push my boundaries. In fact, I had chosen our hike, the unmaintained Porter’s Flat Manway, after consulting a hiking guide to the Smokies which stated, “This is the most difficult trail in this entire guidebook. Don’t do it!”Away we went, up to the crest of the Smokies, the sweat of a late summer afternoon pouring down my temples, the searing sensation in my calves following each step, the wondering when it would be over. It was just like running wind sprints in basketball practice. I hated it. And I loved it.Then the rain came. We donned our ponchos and continued, a combination of sweat and shower soaking my entire body. At the Porter’s Flat campsite, the maintained trail ended. We forged on. The manway was marked with rock cairns, little piles of rock left by previous hikers to show the way.It was starting to get really hard. Did I have it in me?The trailbed steepened, but the rock cairns were still there to guide the way. Then we came to an open jumbled rock field rising up several watery ravines. No cairns were visible. The two of us vainly searched the sloping mountainside for a marker. I hadn’t thought to bring a compass. So we headed straight up the steepest ragged gulch. 1 2
AD Quality Auto 360p 720p 1080p Top articles1/5READ MOREBasketball roundup: Sierra Canyon, Birmingham set to face off in tournament quarterfinalsThe California Teachers Association, which backs Krekorian and apparently won’t even tolerate unwitting dissent from its party line, went ballistic. So did Krekorian. Various other members of the party power base also chimed in. All this because a loyal Democrat with a long history of public service and a commitment to education stumbled over his words. It’s as though Quintero’s offhand remark exposed a subliminal betrayal – a thought crime to partisan extremists who demand ideological purity. With fellow Democrats being this intolerant of each other, is it any surprise that our hyperpartisan legislators do nothing but bicker? This is the sort of extremism that has poisoned California politics. The worst thing about California’s rigged legislative districts is that the public at large doesn’t choose Assembly members and state senators in general elections; the party faithful do it in partisan primaries. The result is a Legislature filled with extremists on both sides who refuse to work together and who get little done. The latest example of this unfortunate trend is the rhetorical thrashing that Glendale City Councilman Frank Quintero is taking in his race against Burbank school board member Paul Krekorian, a fellow Democrat, to succeed Dario Frommer in the 43rd Assembly District. Quintero’s “crime,” if you can call it that: Three weeks ago, in a debate, he mistook vouchers for interdistrict school transfers, and he said he backed the idea. Never mind that Quintero has publicly expressed opposition to vouchers many times before or that he later retracted the inadvertent remark. His slip of the tongue was enough to set off the party’s extremists. 160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set!