Deep Learning Algorithms Help Map Developing Brains

first_img Robot Dog Astro Can Sit, Lie Down, and Save LivesDeepMind’s AlphaStar AI Crushes Pro StarCraft Players Thanks to machine learning, researchers are one step closer to understanding the structure and function of different brain regions.Scientists from the Brain Research Institute of the University of Zurich (UZH) and the Swiss Federal Institute of Technology (ETH) developed a fully automated brain registration method for segmenting gray matter in mice.“My lab aims to reveal how the mammalian brain develops its abilities to process and react to sensory stimuli,” study co-author Theofanis Karayannis told Tech Xplore. “Most of the work we do is on the experimental side, utilizing the mouse as a model system and techniques that range from molecular-genetic to functional and anatomical.”Though initially tested on animals (there’s a reason they’re called “lab rats”), the system—a fully automated convolutional neural network (CNN)-based method called DeNeRD (Detect Neurons in different brain Regions during Development)—could eventually be applied to humans.This study is part of a larger project, including work in which Karayannis and colleagues use deep-learning algorithms to track inhibitory neurons, gauging the development of brain capabilities at specific points in time.“The first step toward this goal is to accurately register the regions of interest in a mouse brain against a standard reference atlas, with minimum human supervision,” according to the research paper. “The second step is to scale this approach to different animal ages, so as to also allow insights into normal and pathological brain development and aging.”Using the computational skills of Ph.D. student Asim Iqbal, the team was able to test some image-registration-based methods gaining traction among neuroscientists.“We quickly realized that existing techniques are suboptimal for cases where the tissue sections are rotated,” Karayannis said. “Or when their geometry is compromised due to methodological issues, for example during brain tissue slicing.”So, they developed their own deep learning method—Segmenting Brain Regions (SeBRe)—to produce reliable results regardless of scale, rotation, and morphological issues, Tech Xplore reported.The group trained their neural network on brain sections of 14-day-old mice, then tested its ability to generate anatomical masks of previously unidentified sections of the brain in four-, 14-, 28-, and 56-day-old mice.“SeBRe outperformed all existing brain registration methods,” according to Tech Xplore.In the future, SeBRe could be used to track and quantify anatomical changes in the developing brain, as well as to identify other information, like which genes are expressed during the growth of a mouse brain.“Hopefully, this study is the beginning of a path that will ultimately allow us and the community to explore alterations in brain structure and function,” Karayannis said. “Not only across different developmental stages, but also in devastating brain disorders, helping to identify new biomarkers and form novel hypotheses about disease generation and progression.”Let us know what you like about Geek by taking our survey. Stay on targetlast_img read more

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Educator inspired retiring Battle Ground superintendent

first_img As a kid, Battle Ground Public Schools Superintendent Mark Hottowe was always small for his grade.It made him a target for teasing, bullying and the kind of harassment he’s made his mission in more than 40 years in education to combat. It wasn’t until high school in Bothell, when a history teacher and coach mentored and supported Hottowe, that he realized he was important — that he could make a difference.“It’s a common story for most people who go into education,” Hottowe, 63, said. “Someone, somewhere in your youth that impacted you and made you feel like you were worthwhile and you could contribute.”Hottowe, whose last day with the school district is Friday, has spent the last 41 years as a teacher and administrator in the Pacific Northwest. Mark Ross, currently the district’s assistant superintendent of teaching and learning, will replace him July 1.Incoming Superintendent Mark Ross’ contract runs from July 1 of this year through June 30, 2020. He will receive a salary of $209,065 plus benefits. Retiring Superintendent Mark Hottowe’s pay and benefits were the same, according to his most recent contract.Hottowe’s career began teaching Native American students in Neah Bay before moving on to become an assistant principal in the Sumner School District, a principal in the Longview School District, the director of student services and the executive director of supervision and human resources for the Kelso School District, and the superintendent of Ocean Beach School District in Long Beach. Mark Hottowe last_img read more

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PM urges WISYNCO to consider alternatives to styrofoam

PM urges WISYNCO to consider alternatives to styrofoam

first_imgFacebook Twitter Google+LinkedInPinterestWhatsApp Related Items: Facebook Twitter Google+LinkedInPinterestWhatsAppKINGSTON, Jamaica, October 19, 2016 – Prime Minister, the Most Hon. Andrew Holness, has urged Wisynco Group Ltd., the sole manufacturer of styrofoam in Jamaica, to consider the development of environmentally friendly alternatives to the product.Following a tour of Wisynco’s White Marl complex in St. Catherine today (October 19), Mr. Holness issued a challenge for the company to identify products within the Jamaican environment that could be creatively used to replace Styrofoam.  He suggested the hemp plant could be utilized in creating a substitute for the product.   “I am challenging you, the captains of industry to see what… can be used to propel innovation, to bring new products to market that create new streams of manufacturing, that employ new people (leading) to more sales, which drive growth,”  he said.The Prime Minister’s tour of the facility follows the Senate’s recent approval of a private member’s motion proposing a ban on Styrofoam and plastic bags.  The motion, brought by Government Senator, Matthew Samuda, noted that Styrofoam and plastics take an inordinately long period of time to break down in the environment, and create a major problem at landfills.  He suggested the use of containers made from cardboard or other biodegradable materials.Mr. Holness, in stating that the Government is pushing for inclusive and sustainable growth, highlighted the problems brought on by inappropriate disposal of plastics and Styrofoam.   He noted that while banning the products may not be the solution, the issue must be debated in keeping with the country’s democratic processes, adding that the discussion will serve to stimulate public discourse on the topic.The Prime Minister, in the meanwhile, commended the company on initiatives it has already taken to reduce the impact of its products on the environment, as well as the move to add a biodegradable component to its foam items, which will allow them to break down in about five years.  “It is good for us to know that you have already started to use technology to ensure that your products are not harmful in the long term to the environment, and I think that should be included in the conversation about the potential ban on Styrofoam,” he said.Mr. Holness said the Government, in the short term, will have to look at ways to improve waste management. He reiterated the intention to pursue a waste-to-energy solution, which he believes will create an economic motive for persons to more adequately manage waste products.Chairman of Wisynco Group Ltd., William Mahfood, in highlighting the steps taken to reduce the company’s carbon footprint, noted that balancing human capital, the environment and business sustainability is important to the entity.  He said it is crucial that a holistic look be taken of the impact that instituting the proposed ban on Styrofoam would have on consumers and the approximately 2,000 employees of the company.  Wisynco Group has been producing Styrofoam for more than 35 years.last_img read more

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Bahamas Crime Report  Two murders counterfeit cash husband critically injured by wife

Bahamas Crime Report  Two murders counterfeit cash husband critically injured by wife

first_imgFacebook Twitter Google+LinkedInPinterestWhatsAppBahamas, June 6, 2017 – Nassau – Two murders in four hours in Nassau as Police report that overnight a shooting victim died in hospital.  They are searching for two suspects in connection to that crime which happened around 9pm.  It is said the man was standing at convenience store on Rosedale Street, off Mackey Street when two men emerged from a truck, with handguns and shot him.  They sped off in a green, single cab Ford Ranger.  The killing earlier on Whit Monday holiday happened on Okra Hill at the home of the victim, shortly before 5pm.  The man was found lying dead on the ground in front of his home and he too was shot.  Police need help in solving these matters.  Police also arrested a Brazilian man for possession of $4,000 in counterfeit US money.  The man was staying at a hotel on Paradise Island and Police, following a lead arrested the man in his room.  It is when officers found the Brazilian to still have a large amount of counterfeit currency in his possession.  That arrest happened yesterday also.  And, a woman was taken into custody after throwing a corrosive chemical on her husband; the man is critical in hospital now.  The pair was arguing at their home on St. Alban’s Drive on Sunday around 3pm.  Police say investigations into the matter, and all others are ongoing.  #MagneticMediaNews#husbandcriticallyinjuredbywife#Bahamascrimereport Facebook Twitter Google+LinkedInPinterestWhatsApp Related Items:#Bahamascrimereport, #husbandcriticallyinjuredbywife, #magneticmedianewslast_img read more

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Emery believes Arsenal and Liverpool are not too far apart

Emery believes Arsenal and Liverpool are not too far apart

first_imgBoth teams are on the top four clubs of the 2018-2019 English Premier League season with only six points of differenceArsenal and Liverpool are currently in 4th and 2nd position, respectively, in the English Premier League.But only six points are what separates both teams. And for the Gunners’manager, Unai Emery, the distance is not big.“Some teams are more advantaged than us. One of which is very clear, Manchester City,” Emery told Sky Sports.“The difference at the moment between Liverpool and [us] is not very big, but it is an important difference also.”divock origi, liverpoolReport: Origi cause Klopp injury concerns George Patchias – September 14, 2019 Divock Origi injury in today’s game against Newcastle is a cause for concern for Jurgen Klopp.Perhaps with one eye on Tuesday’s trip to Italy…“We are now in terms of points, performances and the goals we’re scoring, with Chelsea and Tottenham. This is the reality. We want to progress but we are not thinking of them,” he added.“It’s a big challenge because it is away and we need to improve our mentality away.”“We know we need to change. We need to be more competitive away. I think the team is doing that,” he commented.“It is a new challenge [against United] and the challenge is bigger than other matches.”last_img read more

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Leading Agriculture Organizations Endorse USMCA

first_imgThe National Corn Growers Association, American Soybean Association, National Association of Wheat Growers and National Sorghum Producers today announced their support for the U.S.-Mexico-Canada Agreement (USMCA).Mexico and Canada account for 25 percent of all U.S. agriculture exports and USMCA preserves and builds upon the existing trading relationship between the United States, Canada and Mexico.Members representing the four organizations will be advocating members of Congress to ratify USMCA this year while also urging the Administration to keep the current NAFTA agreement intact until the new agreement is ratified.“Mexico and Canada are the U.S. corn industry’s largest, most reliable corn market; Mexico is corn’s number one buyer and Canada is one of our largest ethanol importers. We cannot afford to risk losing this market,” said NCGA President Lynn Chrisp. “USMCA is NCGA’s top legislative priority for 2019 and we will be working closely with the Administration and members of Congress to get it ratified.”“Passage of USMCA would boost both national and rural economies, and for soybeans, it would assure us tariff-free access to two strong markets, including Mexico, which is our #2 market for whole beans. Under NAFTA, soybean exports to Mexico quadrupled and to Canada doubled. We would like to continue that positive trade momentum with our neighbors,” said Davie Stephens, ASA President and a soybean grower from Clinton, Kentucky.“USMCA includes important provisions for wheat farmers including tariff-free access to imported U.S. wheat for our long-time flour milling customers in Mexico. Further, the Agreement makes important progress toward fixing the grading issue U.S. farmers face when exporting their wheat to Canada,” stated NAWG President and Sentinel, Oklahoma wheat farmer Jimmie Musick. “NAWG, ASA, NCGA, and NSP will continue to work together to get this critical trade deal enacted.””The new USMCA agreement with Mexico and Canada is a win for American producers, and having an agreement in place will safeguard the traditional second largest importer of U.S. sorghum,” said National Sorghum Producers Chairman Dan Atkisson, a sorghum farmer from Stockton, Kansas. “We look forward to expanded market opportunities with Mexico, and urge Congress to pass the measure as soon as possible.”Leaders of the organizations announced their support during Friday’s general session of Commodity Classic, America’s largest farmer-led, farmer-focused agricultural and educational experience.last_img read more

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Diabetes creates cruel irony for hospital guard

first_imgThe Washington State Office of the Insurance Commissioner estimates about 66,000 Clark County residents will be uninsured by Dec. 31, accounting for about 15 percent of the county’s population.For 40 hours a week, Jesse Wolff patrols the grounds of Vancouver’s PeaceHealth Southwest Medical Center, keeping a watchful eye over the patients receiving care and the staff treating them.The 26-year-old security guard’s job presents an unfortunate irony.The Type I diabetic is in desperate need of an insulin pump, but his employer, MetroWatch, doesn’t offer medical insurance. He makes too much money to qualify for state insurance programs. And he can’t afford to purchase insurance coverage or his medication on his own, Wolff said.Doctors told Wolff if he doesn’t get his diabetes under control, within a year he could face a coma or a stroke or heart attack.“It scares me,” he said.Wolff was diagnosed with Type I diabetes in 2008. Type I diabetes is when a person’s body is incapable of producing insulin. As a result, Type I diabetics must rely on insulin injections or an insulin pump, which delivers insulin 24 hours a day through a catheter placed under the skin.last_img read more

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SW MiamiDade homeowner shot at after pursuing burglars

SW MiamiDade homeowner shot at after pursuing burglars

first_imgOrtix’s stepson, Joe Cerna, said the burglars were lucky he wasn’t there. “They’re lucky I didn’t get there before them, because I carry,” said Cerna. “I would’ve shot them.”Miami-Dade Police set up a perimeter and used K-9 officers as well as their SWAT team in an attempt to track down the burglars, but the two men got away. One neighbor said his security camera footage showed the suspects, but police have not released the video as yet.For now, Cerna is just relieved to know his stepfather is OK. “I mean, if somebody takes your stuff, you’re going to fight for it, you know. You’re not going to put your arms down and be like, ‘Oh, all right.”‘Police are asking for the public’s help in locating the two suspects. If you have any information on this home burglary, please call Miami-Dade Crime Stoppers at 305-471-TIPS. Remember, you can always remain anonymous, and you may be eligible for a $1,000 reward.Copyright 2019 Sunbeam Television Corp. All rights reserved. This material may not be published, broadcast, rewritten or redistributed. SOUTHWEST MIAMI-DADE, FLA. (WSVN) – A home burglary in Southwest Miami-Dade turned violent when a suspect pulled out a gun and fired at the homeowner, Monday afternoon.According to police, two armed burglars targeted a home located along Southwest 285th Terrace.The two men broke into the home through a back window and ransacked the house. Homeowner Filon Ortix, who arrived moments later, believes the two men were in his home for approximately 10 minutes before they fled on foot.However, Ortix did not want to let the suspects get away. “I went to Lowe’s, and I came back and saw the door open,” said Ortix. “When I got here, they were leaving my house. I tried to grab them, but they left.”As the homeowner chased down the burglars, one of the men started shooting at him. Ortix was just inches away from being hit. “When I found them over there, I tried to grab them, and that’s when they pulled a gun at me and fired at me,” he said.“I just heard eight gunshots,” said a nearby witness.Ortix showed 7News one bullet hole in the side of his car but said it was only one of seven they shot at him. last_img read more

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Bethel hopes housing initiative may help retain city workers

first_imgJobs in rural Alaska are often seen as a career stepping stone. Professionals take a job for a year, maybe two, and leave. In doing so, they take career skills and experience with them rather than investing those assets back into the community. This high turnover rate prevents institutional knowledge from accumulating and community trust in its professionals from strengthening. How to break this cycle and retain workers persists as one of rural Alaska’s most vexing puzzles. The community of Bethel thinks it’s got one piece figured out.Download AudioWalking into the room, the first thing I notice is the view—a fringe of willows and then miles of snowy tundra. The window belongs to one of six new apartments, specifically constructed for public safety, education and health professionals in Bethel.The idea is by providing high quality, affordable housing, Bethel can better recruit and retain personnel.Bethel Community Services Foundation led the project. The group wants to address community issues, and Executive Director Michelle DeWitt says housing sits high on that list.“When people leave positions here,” DeWitt said, “housing is often at the root of one of their challenges or one of their areas of dissatisfaction. We have a lack of new, appropriate, nice housing.”These apartments are extremely nice— wood pattern floors and cabinets, modern appliances, high energy conservation ratings, and of course, the scenic views.Mayor Rick Robb was also impressed.“Well this is beautiful,” Robb said. “There’s no doubt. Course it’s brand new, all redone, so it’s beautiful. This was kind of a white elephant, kind of an albatross. It’s been totally renovated.”The Willow Place Apartment’s entryway. (Photo by Dean Swope / KYUK.)The building was once a day-care center, left vacant several years ago. The push to revitalize an older building helped attract one of the project’s funders— the Alaska Housing Finance Corporation, or AHFC.For over a decade, the corporation has funded housing projects for teachers, health professionals, and public safety workers across rural Alaska, all in an effort to decrease turnover. So far, the program has shown success with teacher retention.Derrick Chan is a planner with the AHFC and says the key to keeping workers long term is getting them to stay past their first year.“If a person works in an area beyond that one year period,” Chan said, “they’re less likely to transition out. We’re really trying to provide an environment where they can call home, and at the end of the day, they have a place to kick their feet up. They feel welcome.”Bethel City Manager Ann Capela said that initial welcome can make or break a new employee’s first impression.“This is a true story. We had an employee come, take a job at Bethel. We had no place to put him up for the night. We put him up at the annex. He looked at his surroundings, and he left on the first flight in the morning,” Capela said.The city’s newest hire—a fire fighter EMT—will have a different experience. He arrived this week with his family and moved directly into one of the units. It’s a step up from the fire department’s usual protocol of housing new recruits in the fire station for their first month.Fire Chief Bill Howell hopes the apartments will attract more workers.“I would think this is definitely helpful from a recruiting standpoint,” Howell said. “You know, a lot of the times, people have the financial resources to get housing in Bethel, and they just can’t find it.”DeWitt said she’ll consider the housing successful if people stay past one year.“I’d be really excited if we had people who were in the units for 18 months to two years,” DeWitt said, “and I’d be even more excited if they left the units to purchase a home in our community. Retention is a really positive thing. When you have quality people in important positions, the outcomes are better for everyone.”The units opened on Monday, Nov. 30, and already four of the six spaces are occupied. Tenants include the fire fighter, two police officers, and a community safety patrol officer and their families.last_img read more

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US school shooter nonemotional lawyer says

US school shooter nonemotional lawyer says

first_imgDaniel Hernandez, a local imam, prays with his two sons near the site of the shooting at the Santa Fe High School, in Santa Fe, Texas, US, 19 May 2018. Photo: ReutersThe 17-year-old student charged with killing 10 people when he opened fire in an art class at his Houston-area high school appeared “weirdly non-emotional” on the morning after the rampage, one of his lawyers said on Saturday.The teenager, identified by law enforcement as Dimitrios Pagourtzis, has been charged with capital murder and is being held without bail in Santa Fe, Texas, where authorities said he went on a shooting spree shortly before 8 a.m. CDT on Friday.In addition to 10 fatalities, the gunman wounded at least 13 people, with two of them in critical condition. One of those in critical condition was one of the two school resource officers who engaged the shooter before his surrender.Nicholas Poehl, one of two lawyers hired by the suspect’s parents to represent him, told Reuters he had spent a total of one hour with Pagourtzis on Friday night and Saturday morning.”He’s very emotional and weirdly nonemotional,” the attorney said when asked to describe his client’s state of mind. “There are aspects of it he understands and there are aspects he doesn’t understand.”As the shooting unfolded, Pagourtzis spared people he liked so he could have his side of the story told, a charging document showed.While authorities have given no indication why he apparently targeted the art class, a mother of one of the victims told the Los Angeles Times that her daughter, Shana Fisher, 16, had rejected four months of aggressive advances from Pagourtzis.Fisher finally stood up to him and embarrassed him in class, the newspaper quoted her mother Sadie Rodriguez as writing in a private message to the Times.”A week later he opens fire on everyone he didn’t like,” she said. “Shana being the first one.”Rodriguez did not say how she knew her daughter was the first victim, according to the newspaper.Rodriguez could not independently be reached for comment.Family of shooter speaksPagourtzis’ family said in a statement they were “saddened and dismayed” by the shooting and “as shocked as anyone else” by the events. They said they are cooperating with authorities.”While we remain mostly in the dark about the specifics of (Friday’s) tragedy, what we have learned from media reports seems incompatible with the boy we love,” the family said.Investigators had seen a photo of a T-shirt that read “Born to Kill” on the suspect’s Facebook page and authorities were examining his journal, Texas Governor Greg Abbott told reporters, but there were no outward signs he had been planning an attack.Pagourtzis waived his right to remain silent and made a statement to authorities admitting to the shooting, according to an affidavit ahead of his arrest.Asked if Pagourtzis had provided authorities with information about the shootings, Poehl said: “Honestly because of his emotional state, I don’t have a lot on that.”Students retrieve belongingsSanta Fe High School, southeast of Houston, became the scene of the fourth-deadliest mass shooting at a U.S. public school in modern history, joining a long list of campuses where students and faculty have fallen victim to gunfire.The Texas rampage again stoked the country’s long-running debate over gun ownership, three months after a student-led gun control movement emerged from a mass shooting in Parkland, Florida, which left 17 teens and educators dead.Students and faculty, bussed on to campus in small groups, were allowed to enter the high school on Saturday to retrieve belongings, though investigators closed off part of the grounds. Police kept reporters about 100 yards (91 metres) away.All schools in the Santa Fe school district will remain closed on Monday and Tuesday, officials said.In a letter to parents dated Friday but posted on the district’s website on Saturday, Superintendent Leigh Wall said eight of the dead were students and two were teachers. Authorities had earlier said that nine students and one teacher were killed.National Football League star J.J. Watt, who plays defensive end for the Houston Texans, said he will pay for the funerals of the deceased, local media reported.”Absolutely horrific,” he tweeted about the shooting.’Quiet loner’ in a trench coatClassmates at the school of some 1,460 students described Pagourtzis as a quiet loner who played on the football team. On Friday, they said he wore a trench coat to school on a day when temperatures topped 90 degrees Fahrenheit (32 degrees Celsius).Texas’ governor told reporters that Pagourtzis obtained firearms from his father, who had likely acquired them legally, and also left behind explosive devices.Abbott said Pagourtzis wanted to commit suicide, citing the suspect’s journals, but did not have the courage to do so.Some aspects of the shooting had echoes of the massacre at Columbine High School in Colorado in 1999. The two teenaged killers in that incident wore trench coats, used shotguns and planted improvised explosives, killing 10 before committing suicide themselves.It was the second mass shooting in Texas in less than seven months. A man armed with an assault rifle shot dead 26 people during Sunday prayers at a rural church last November.last_img read more

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Doctor gets 5year jail term for assaulting minor

Doctor gets 5year jail term for assaulting minor

first_imgKolkata: A homeopathy doctor has been sentenced to five years imprisonment for sexually assaulting an eight-year-old girl inside his clinic. The incident took place on September 19, 2018. The minor girl had visited the accused doctor, Partha Hue, because of severe stomach pain.Sources informed that the girl was accompanied by her grandmother. For consultation, they both had stepped inside the doctor’s chamber but Hue allegedly asked the grandmother to wait outside. After a few minutes, when she heard her granddaughter crying and asked the reason, the doctor allegedly informed that it was because of the stomach pain. Also Read – Speeding Jaguar crashes into Mercedes car in Kolkata, 2 pedestrians killedLater, when they went home, the girl narrated the incident. On September 24, the girl’s mother lodged a complaint against Hue at Beniapukur police station. Upon receiving the complaint, police acted promptly and arrested Hue. He was booked under sections of the Indian Penal code and Protection of Children from Sexual Offences (POCSO) Act. The sleuths submitted a charge-sheet against Hue in the court along with the recorded statements and medical reports.last_img read more

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GOG Galaxy review

GOG Galaxy review

first_imgGOG Galaxy review by Martin Brinkmann on June 05, 2018 in Games – Last Update: June 05, 2018 – 6 commentsGOG Galaxy is a gaming client for PC and MAC OS X by GOG. Unlike Steam, it is completely optional for GOG customers who can download and play purchased games without the program as well.If I had to pick a games store on the Internet, I’d select GOG over any other store out there because of its stance on DRM, and Dollar to Euro handling of game prices.While I love GOG, it is not the Store that I use the most. The main reason for that is that its catalog is tiny in comparison to that of Steam. GOG offers mostly classic computer games and independent games on its store.I downloaded GOG games manually to my systems and played them as if they were independent games before the initial release of GOG Galaxy. The process changed with the release of the gaming client as it centralized management of all GOG games and features nice-to-have features such as storing savegames in the cloud, bandwidth limits, auto-update options, rollback support, and community and friends features.Customers can ignore the client and run games individually instead if they prefer that.GOG GalaxyGOG Galaxy is available for Windows and Mac OS X currently. Windows users can install the client and sign in to the GOG account to start using it.If you have GOG games on the computer already, you may want to use the “scan and import folders” feature to add games to the Galaxy client so that they don’t need to be downloaded and installed again.You may want to check the settings on first start to make sure all are set to your liking. You get to control global features such as the default installation language and folders, the game overlay, bandwidth restrictions, cloud saves, achievements, or auto updates there.Some of the features can be turned off for individual games as well. If you don’t want a particular game to update automatically or push saves to the cloud, you can disable those options in the game configuration menu.The Galaxy client comes with a built-in store and library management among other features. You can browse your existing library with a click on the library menu item in the interface, and filter games by platform as well if you want to.Search and other filters are provided to find games quickly. A click on any game opens the details view in the client.It includes a description and activity information, and options to install the game if it is not installed already.The installation dialog provides the following options:Select a location on the local computer system to install the game to. Default is GOG Galaxy\Games on the installation drive.Select the desired game language if multiple languages are supported.Configure auto-updating behavior.Create a desktop shortcut for quick access.Any game that you install is listed in the sidebar for quick access. Just select it and hit the play button to start playing right away.Access to additional content, game manuals, soundtracks, wallpapers, and other items is provided in the client directly.One useful feature of GOG Galaxy is the client’s rollback feature. On Steam, if a game update breaks things you cannot really do anything about that. On Galaxy, you simply pick an earlier version of the game and roll back to it.The rollback feature makes game updates less of a problem as you can always go back to a previous version if they break something.Most GOG games are not updated often which in turn means that you won’t experience as much breakage as on other platforms. The main reason for that is that you won’t find most mainstream full price games on GOG but mostly independent games (which may update frequently) and classic games (which usually don’t).Galaxy comes with community features such as friends lists and other social features such as achievements and multiplayer integration for games that support GOG’s implementation.I have not used these features up until now due to a lack of friends using the client and lack of games support. When it comes to multiplayer, Steam, Battle.net, uPlay or Origin are the platforms that are used for that. Still, the integration of multiplayer and friends functionality opens up the possibility that GOG will one day become a contender. All it probably takes is one exclusive popular game to push multiplayer functionality.Closing WordsGOG Galaxy is a convenient optional client for the GOG platform that centralizes game management first and foremost. It gives users more control over games and includes several nice to have features such as rollback options or auto-updating of games.The one thing that is holding GOG back is games support. While it is heaven for classic games and many independent games, it is not the place to go if you are looking for new Triple A games that are not produced by CD Project (which owns GOG).Now You: What’s your take on GOG and GOG Galaxy?Summary12345 Author Rating5 based on 11 votes Software Name GOG GalaxyOperating System WindowsSoftware Category GamesLanding Page https://www.gog.com/galaxy Advertisementlast_img read more

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Ian McKellen wants you to watch Englands World Cup semifinal in technicolor

Ian McKellen wants you to watch Englands World Cup semifinal in technicolor

first_imgGot a news tip? Want to share your story? Email us . Share this:TwitterFacebookLike this:Like Loading… Tonight, like every Monday, “Quiz Night” @TheGrapesLondon. My team was second last week, and second the week before. pic.twitter.com/lSurdY0C7J— Ian McKellen (@IanMcKellen) April 27, 2015The match at The GrapesEstablished in 1583, The Grapes is located in a Grade II listed building in Limehouse, East London. To add to its quirky history, Victorian author Charles Dickens’ described the pub in the opening chapter of his novel Our Mutual Friend written in 1864-65.More than 150 years later, the pub will be among the preferred venues for Londoners to watch the World Cup.The Grapes, owned by Sir Ian McKellen in partnership with theatre and film director Sean Mathias, and Evgeny Lebedev, publisher of UK newspaper Evening Standard. | Photo: Wikipedia CommonsCroatia v EnglandTonight’s game at Luzhniki Stadium is crucial. If they lose, England will play Belgium for the third place position on 14 July. If England wins, however, the team will go straight to the final against France on 15 July. It will be their first appearance in a World Cup final since 1966.As much as we would love to watch anything with Sir Ian McKellen – whether in black and white or in technicolor – we must warn you: he might not be there. Although he has been spotted serving his customers the occasional pint and bowl of chips from time to time, there is no guarantee the Lord of the Rings actor will be at The Grapes tonight. It will be up to the fellowship of his most loyal fans to find out.You might also like:Ian McKellen shares another amazing throwback pic of himself in his 20s Family Guy’s Stewie to reveal sexuality to therapist Ian McKellenIan McKellen leads protest outside Russian Embassy over Chechnya persecution of gay menIan McKellen: It’s ‘un-American’ for Trump not to protect LGBTI rightsRead the full article on Gaystarnews:  :https://www.gaystarnews.com/article/ian-mckellen-wants-you-to-watch-englands-world-cup-semi-final-in-technicolor-at-his-pub/ The openly gay British thespian and national treasure is among the owners of The Grapes, a cozy pub on the north bank of the Thames. It will screen the match at 7pm.An official invite from Ian McKellenMcKellen tweeted to his followers this morning, encouraging them to go and watch the match at the pub. Furthermore, he proved his hashtag game to be particularly strong.Watch the semi final at The Grapes #Limehouse We’ve set up a Colour (!) TV at the bar. #ItsComingHome https://t.co/g7i3vi0kCU— Ian McKellen (@IanMcKellen) July 11, 2018‘We’ve set up a Colour (!) TV at the bar,’ the tweet reads enthusiastically. Perhaps a cheeky, vintage hint to the 1966 World Cup, the last time the World Cup was hosted by England? The Three Lions won that time around, so McKellen’s time-traveling tweet might be good luck.It’s Coming HomeThe hashtag #ItsComingHome is also a shout out to England’s football team. The refrain of Three Lions, a 1996 song by the Britpop band Lightning Seeds, ‘It’s coming home’ referred to England hosting the UEFA Euro Cup on that year and literally bringing the football back home for the first time after 1966.It has become a popular slogan during football competitions ever since and fans may howl it tonight at McKellen’s pub. eTN Chatroom for Readers (join us) GAYSTARNEWS- Sir Ian McKellen played the role of Gandalf in the Lord of the Rings and The Hobbit trilogies. | Photo: LOTR/New Line Ahead of tonight’s World Cup soccer semi-final which will see England go up against Croatia, actor Ian McKellen invited fans to watch the game at his London pub.last_img read more

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Update Bikers bid farewell to Shaun

Update Bikers bid farewell to Shaun

first_imgDID YOU KNOW?Click on the words highlighted in red to read more on this and related topics.If you are reading this on your cellphone and there are telephone numbers provided in the text, you can call these simply by clicking on them.To receive news links via WhatsApp.For the latest news, visit our webpage or follow us on Facebook and Twitter. Join us there! WebsiteWebsiteWebsite WebsiteWebsiteWebsite WebsiteWebsiteWebsite Speaking on behalf of fellow bikers, Jose Hilton said, “Beans’ death has left many of us still coming to terms with his passing. He was always a safe rider and respected his bike. He rode for passion and never belonged to any club. A remarkable person of good character, friendly and always there to assist.”Shaun worked at NN Alarms (armed response) and had a reputation for his unflinching determination when it came to fighting crime and doing his job to the best of his ability. Criminals would not dare cross his path!Ladysmith is still reeling after the sad news of his untimely passing – a great loss indeed.Ramesh “Shaun” Ramdhani will be dearly missed by his family, friends and the community at large.center_img Hundreds attended the funeral of Ladysmith icon 35-year-old Ramesh “Shaun” Ramdhani this afternoon (Tuesday).Motor vehicles and motorcycles gathered on either side of Willow Drive and nearby streets. People throughout Northern KwaZulu-Natal and as far as Johannesburg attended the funeral to pay their last respects.Memorable moments of Shaun’s life were screened via a projector, and farewell songs were softly played, leaving many in tears.There was revving of engines and throttling of gears as fellow bikers rode along the streets from Shaun’s home in Willow Drive to the crematorium as part of the bike procession.Shaun, also known as “Beans” and “Ramoo”, lost his life in a tragic motorbike accident on the N11 on Sunday evening. The accident occurred approximately 10km outside of Newcastle, where it is believed that a vehicle overtaking a truck hit the motorbike that Shaun and a passenger were on.Paramedics attempted to resuscitate the 35-year-old, but unfortunately he did not respond to their efforts.Shaun owned a 2006 Honda 600RR motorbike and has been riding for many years.last_img read more

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Loyola Medicine Conducts Successful See Test Treat Free Cancer Screening

Loyola Medicine Conducts Successful See Test Treat Free Cancer Screening

first_img September 9, 2015 — More than 50 women in need received free cervical and breast cancer screenings with same-day results as part of a recent See, Test & Treat program and health fair at Loyola University Medical Center. Funded by a grant from the College of American Pathologists (CAP) Foundation, this was the first See, Test & Treat program offered in Illinois.“Many of the women we cared for had not had a Pap test or mammogram in more than 20 years, and thanks to the generous funding by the CAP Foundation, were able to receive care,” said Loyola Chair of Pathology Eva M. Wojcik, M.D., FCAP. “Seeing those signs of relief on the faces of women who were told their screenings came back normal was priceless.”Wojcik led a team of more than 35 Loyola physicians and medical personnel for the cancer screenings. Women between the ages of 30 and 64 with Medicaid or who were uninsured qualified for the event.The screening included a pelvic exam, a Pap test with same-day results, an HPV test, a breast exam and screening mammography, if appropriate. Displays and educational materials were also available to help women better understand their unique health needs. Financial and medical specialists were onsite to interact with participants, answer questions and provide information.Through pathologists at select institutions around the United States, the See, Test & Treat program has provided free cervical and breast cancer screenings to thousands of women. The program is funded by donations to the CAP Foundation. The CAP Foundation plans to expand See, Test & Treat so that more pathologists can collaborate with their clinical colleagues to coordinate care teams and provide essential screening services to more vulnerable women across the country.The Loyola University Medical Center event was also supported by Hologic Inc., the Community Memorial Foundation, the Coleman Foundation and Quest Diagnostics.For more information: www.cap.org FacebookTwitterLinkedInPrint分享 Technology | Artificial Intelligence | July 18, 2019 Paragon Biosciences Launches Qlarity Imaging to Advance FDA-cleared AI Breast Cancer Diagnosis System Paragon Biosciences LLC announced the launch of its seventh portfolio company, Qlarity Imaging LLC, which was founded… read more Related Content Technology | Breast Biopsy Systems | July 24, 2019 Fujifilm Releases Tomosynthesis Biopsy Option for Aspire Cristalle Mammography System Fujifilm Medical Systems U.S.A. Inc. recently expanded its breast imaging solutions with the launch of its… read more News | Mammography Reporting Software | July 26, 2019 Ikonopedia Releases Automated Combined Reporting Package at AHRA Ikonopedia showcased its recently released Automated Combined Reporting package and its entire suite of structured… read more News | Artificial Intelligence | August 13, 2019 Artificial Intelligence Could Yield More Accurate Breast Cancer Diagnoses University of California Los Angeles (UCLA) researchers have developed an artificial intelligence (AI) system that… read more IBM collected a dataset of 52,936 images from 13,234 women who underwent at least one mammogram between 2013 and 2017, and who had health records for at least one year prior to the mammogram. The algorithm was trained on 9,611 mammograms. Image courtesy of Radiology. Qlarity Imaging’s software is used to assist radiologists in the assessment and characterization of breast lesions. Imaging features are synthesized by an artificial intelligence algorithm into a single value, the QI score, which is analyzed relative to a database of reference abnormalities with known ground truth. Image courtesy of Business Wire. News | Ultrasound Women’s Health | July 11, 2019 FDA Clears Koios DS Breast 2.0 AI-based Software Koios Medical announced its second 510(k) clearance from the U.S. Food and Drug Administration (FDA). Feature | Artificial Intelligence | July 19, 2019 | Michal Chorev AI Models Predict Breast Cancer With Radiologist-level Accuracy Breast cancer is the global leading cause of cancer-related deaths in women, and the most commonly diagnosed cancer… read more News | Mammography | September 09, 2015 Loyola Medicine Conducts Successful See, Test & Treat Free Cancer Screening Event funded by the College of American Pathologists Foundation helps vulnerable women in underserved communities improve their health Technology | Mammography Reporting Software | July 25, 2019 Hologic Partners With MagView to Develop Unifi EQUIP Solution Hologic announced a partnership with mammography information solutions provider MagView to develop Unifi EQUIP, an… read more News | Mammography | August 14, 2019 Imago Systems Announces Collaboration With Mayo Clinic for Breast Imaging Image visualization company Imago Systems announced it has signed a know-how license with Mayo Clinic. The multi-year… read more News | Breast Imaging | August 02, 2019 Volpara to Distribute Screenpoint Medical’s Transpara AI Solution Volpara Solutions and ScreenPoint Medical BV signed an agreement under which Volpara will sell ScreenPoint’s Transpara… read more Image courtesy of Imago Systems News | PACS | August 09, 2019 Lake Medical Imaging Selects Infinitt for Multi-site RIS/PACS Infinitt North America will be implementing Infinitt RIS (radiology information system)/PACS (picture archiving and… read more read morelast_img read more

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Why some people are more prone to mosquito bites than others

first_imgNo related posts. Mosquito season is in full swing. A lucky few people seem immune to the bites of the pesky insects. Others can’t seem to avoid them.In Costa Rica, as the rainy season continues its shaky start, the number of dengue cases are soaring. The latest figures from the World Health Organization (WHO) show Costa Rica with 11,672 reported cases of dengue so far this year, which is not updated to the latest bulletin from the Costa Rican government, which reports 14,929 cases.Some may be more at risk than others. New research explains mosquitoes’ apparent selectivity. According to an article in Smithsonian magazine, an estimated 20 percent of people are “especially delicious” to mosquitoes. (Shudder.) They are bitten more often than others.Why? A number of factors are at play. Chief among them is blood type. “Not surprisingly — since, after all, mosquitoes bite us to harvest proteins from our blood — research shows that they find certain blood types more appetizing than others,” the article reports. Type O is at the top of the list. Additionally, about 85 percent of people secrete a chemical signal that indicates their blood type; these “secretors” are more prone to bites regardless of their blood type.Another factor is the amount of carbon dioxide people emit when they breathe. Larger people exhale more of the gas, which may explain why adults tend to get bitten more often than children. This also means that obese people are more prone to getting bitten than average or underweight people, tall people more prone than short. Sweat, high body temperatures and skin bacteria also play a role. Pregnancy, which increases body temperature and carbon dioxide emission, may also increase the likelihood of bites.And if you’re enjoying a beer at a barbecue, you may have made yourself a mosquito target. No one has been able to pinpoint why drinking beer makes people more attractive to mosquitoes. Some have theorized that the elevation in body temperature and the amount of ethanol in sweat may play a role, but neither theory has panned out. Still, it appears that even a 12-ounce bottle is enough to do the trick.© 2013, The Washington Post Facebook Commentslast_img read more

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liquidationVenture Farwholesalers

liquidationVenture Farwholesalers

first_imgliquidationVenture Farwholesalers Liquidators have been appointed to place the Venture Far company into liquidation, after 39 years of operation.The company says the costs and challenges of being a boutique wholesaler, operating in a highly price driven, low margin industry have proven to be too large to overcome.“Venture Far identified the need to adapt with the changing travel landscape and underwent major changes in 2017 including a total re-brand. While we saw improvements from these changes, it has proven not to be enough.”For Agent queries regarding your bookings, please contact 1300 303 343 and select option 1. The Liquidators have maintained some reservations staff to assist with your queries. Sales, Marketing and Product areas have ceased immediately.For queries regarding the liquidation, please contact venture@balanceinsolvency.com.aulast_img read more

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Former Cardinals kicker Phil Dawson retires

Former Cardinals kicker Phil Dawson retires

first_img Former Cardinals kicker Phil Dawson retires Kurt Warner will not be entering the Pro Football Hall of Fame this weekend.No, the player who threw 208 touchdown passes for the St. Louis Rams, New York Giants and Arizona Cardinals will watch as the Class of 2016, which includes Brett Favre, Tony Dungy, Kevin Greene, Marvin Harrison, Orlando Pace, Eddie DeBartolo Jr., Ken Stabler and Dick Stanfel is enshrined in Canton, Ohio.Maybe one day, Warner will get the call and have his very own bust. Until then, he will remain near the top of most lists that talk about the best players who are not in the Hall of Fame, and probably should be. Top Stories 0 Comments   Share   The 5: Takeaways from the Coyotes’ introduction of Alex Meruelo Derrick Hall satisfied with D-backs’ buying and sellingcenter_img Add in the teams he took to the Super Bowl and yeah, no one would argue if he was inducted. – / 21 (AP Photo) Recently, ESPN’s Kevin Seifert ranked 10 players who he thinks should be in the Hall of Fame, and Warner came in at No. 2 behind only Terrell Owens.Warner was his team’s primary starter (as defined by starting more than half of its games) in only eight seasons, so his cumulative statistics fall short of most modern-day Hall of Fame quarterbacks. (He ranks No. 35 in league history in touchdown passes and No. 36 in yards.) But Warner made those seasons count. Most notably, he is one of only three quarterbacks to take two teams to the Super Bowl. That those franchises — the St. Louis Rams and Arizona Cardinals — were previously, and at times subsequently, moribund should not be forgotten. Finally, he was arguably the most accurate quarterback of his generation, and one of the best in league history. Warner has the NFL’s second-best career completion percentage (65.5) among quarterbacks with at least 100 starts.Warner’s case is indeed legitimate.Though his career did not last as long as some of the other all-time greats, he did throw for 32,344 yards and 208 touchdowns with just 128 interceptions. He was a four-time Pro Bowler, two-time First Team All-Pro selection, an MVP and a Super Bowl MVP. Grace expects Greinke trade to have emotional impactlast_img read more

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Go back to the enewsletter San Francisco startup

first_imgGo back to the e-newsletterSan Francisco start-up and manufacturer of design-centric private aircraft – Cobalt – has designed a plane without dials, gauges and switches, but equipped with a forewing that makes it nearly impossible to stall mid-air and a high-tech tablet control system.Pre-orders can now be placed for the Co50 Valkyrie and Valkyrie-X. The Cobalt Valkyrie-X is an experiential version, which is only available in the US, while the Co50 Valkyrie is the fully certified model and offered worldwide.Cobalt CEO David Loury said he wanted build a plane that was easier and safer to fly: “Ten years ago, I had a vision to disrupt the aviation industry with an innovative private aircraft, that is not only technologically sound and safe, but also design-centric and luxurious. It’s a world class aircraft, complete with advanced safety, technology, and modern design features for travel-loving consumers and aviation enthusiasts.”The aircraft’s are both five-seat, propeller-driven private planes designed with three iPad-style screens that display the most essential information.Go back to the e-newsletterlast_img read more

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Go back to the enewsletter Sherwood Suites one o

first_imgGo back to the e-newsletterSherwood Suites, one of the newest and plushest apartment-only properties in Ho Chi Minh City is positioned as a family favorite due to its spacious suites, child-friendly facilities and convenient location just next to the busy central district.Travelling to Vietnam’s southern hub with a family is becoming an increasingly popular option. According to Sherwood Suites GM Janet Fitzner, “Rooms in even the finest hotels in the city are often too small to fit multiple people comfortably, while the option of reserving an adjoining room only adds to the costs while failing to address a sense of separation. We offer a luxurious, spacious option ideally suited to families.”Ho Chi Minh City has numerous compelling attractions for adults and kids alike such as its fantastic food culture, an array of cultural sights and a general air of dynamism and charisma. It is also a logical hub for exploring Vietnam. Sherwood Suites is making it easier for families to experience these attributes in style and safety.The apartment-only arrangement at the property includes 157 suites varying from studios to one- and two-bedroom configurations and penthouses. Room sizes for the family start at a generous 81 square metres and extend to 118 square metres, making them perfect for families ranging between three and six persons.Other family-friendly features in the apartments include fully equipped kitchens ideal for rustling up snacks and meals, a washing machine and dryer to help keep on top of laundry and a living room with dining table where the family can share dinner or kick back and watch a movie on the flat-screen SMART television.All rooms feature elegant furniture from renowned brand B&B Italia, mattresses by Simmons of England as well as fully equipped kitchens, marble-lined bathrooms with bathtub, walk-in rainforest showers and premium toiletries, floor-to-ceiling windows and free access to high-speed Wi-Fi.While apartments are very much a home away from home, facilities at the property are the equal of any luxury hotel in Ho Chi Minh City. Five-star amenities include an outdoor covered pool, family size Jacuzzi, an international restaurant, a lobby and pool bar and an expansive 24-hour gym with sauna and steam room. Specific niceties for families, meanwhile, include a games’ room with billiards table and table football and a kids’ playroom.Another advantage of the property is its location in leafy District 3. One of the city’s most sought-after areas, it is distinguished by attractive French colonial villas and mature trees. It’s a peaceful alternative to the pulsing energy of the city’s central District 1, while remaining just a short hop away from downtown.“Instead of making compromises on space or spending double the money on an adjoining room at a luxury hotel, families can enjoy the space of a fully equipped apartment while enjoying the services and facilities of a five-star hotel,” adds Fitzner.Go back to the e-newsletterlast_img read more

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